Adriamycin nephropathy: A model of focal segmental glomerulosclerosis
نویسندگان
چکیده
منابع مشابه
Aristolochic acid nephropathy complicating a patient with focal segmental glomerulosclerosis.
A 75-year-old Chinese male was admitted to hospital with a 1 week history of ankle oedema, facial puffiness and frothy urine. He had no sore throat, smoky urine, rash, joint pain, fever, night sweat or weight loss. He did not experience shortness of breath. Five weeks before, he was admitted for insidious onset of rightsided weakness with a 1 year history of chronic neck pain after an accidenta...
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Focal segmental glomerulosclerosis (FSGS) is a leading cause of kidney disease worldwide. The presumed etiology of primary FSGS is a plasma factor with responsiveness to immunosuppressive therapy and a risk of recurrence after kidney transplant-important disease characteristics. In contrast, adaptive FSGS is associated with excessive nephron workload due to increased body size, reduced nephron ...
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Idiopathic focal segmental glomerulosclerosis (FSGS) is a primary glomerular disease that essentially represents a form of chronic, progressive renal fibrosis for which there is no discernible cause. Often presenting with or eventually manifesting the nephrotic syndrome, this disease is increasing in incidence in both children and adults. Therapy continues to be a challenge, although some patie...
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Background and objectives: Treatment with IFN is rarely associated with nephrotic syndrome and renal biopsy findings of minimal-change disease or FSGS. Design, setting, participants, & measurements: We report 11 cases of collapsing FSGS that developed during treatment with IFN and improved after discontinuation of therapy. Results: The cohort consists of seven women and four men with a mean age...
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Focal segmental glomerulosclerosis (FSGS) represents the most common primary glomerular disease responsible for the development of end-stage renal disease (ESRD) in the United States (US). The disease progresses from podocyte injury to chronic kidney disease (CKD), ultimately leading to total nephron degeneration. Extensive basic science research has been conducted to unwind the mechanisms of F...
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ژورنال
عنوان ژورنال: Nephrology
سال: 2010
ISSN: 1320-5358
DOI: 10.1111/j.1440-1797.2010.01383.x